Skip to main content
Log in

Analysis of the longitudinal course of PTSD in 716 survivors of 10 disasters

  • Original Paper
  • Published:
Social Psychiatry and Psychiatric Epidemiology Aims and scope Submit manuscript

Abstract

Purpose

Identification of consistent predictors of the temporal course of PTSD has been hampered by non-uniform definitions of onset and remission. Onset and remission of PTSD based on different definitions were examined in a large database of systematically assessed disaster survivors.

Methods

Directly exposed survivors of 10 disasters were studied within approximately 3 months of the disasters and again 1–3 years later, using consistent methods including full diagnostic assessment, allowing aggregation of data from different disasters into a unified database of 716 survivors.

Results

Application of existing definitions of PTSD onset and remission uncovered problems with definitions based on diagnostic threshold as well as onset/remission of symptoms. Few predictors of timing of onset and PTSD remission were identified. Regardless, PTSD symptom group C was found to be pivotal to processes involved in both onset and remission of the disorder.

Conclusions

Research findings related to the onset and remission of PTSD are highly dependent on the definition used. Both symptom-based and diagnostic threshold-based definitions are problematic. Definitions of the onset and remission of PTSD might be more effectively based on the onset and remission of group C symptoms.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
€32.70 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price includes VAT (Sweden)

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. American Psychiatric Association (2000) Diagnostic and statistical manual of mental disorders, 4th edition, text revision. American Psychiatric Association, Washington

  2. American Psychiatric Association (2012) G 05 Posttraumatic stress disorder. http://www.dsm5.org/ProposedRevisions/Pages/proposedrevision.aspx?rid=165. Accessed 1 July 2012

  3. Andrews B, Brewin CR, Philpott R, Stewart L (2007) Delayed-onset posttraumatic stress disorder: a systematic review of the evidence. Am J Psychiatry 164:1319–1326

    Article  PubMed  Google Scholar 

  4. Andrews B, Brewin CR, Stewart L, Philpott R, Hejdenberg J (2009) Comparison of immediate-onset and delayed-onset posttraumatic stress disorder in military veterans. J Abnorm Psychol 118:767–777

    Article  PubMed  Google Scholar 

  5. Blake DD, Weathers FW, Nagy LM, Kaloupek DG, Klauminzer G, Charney DS, Keane TM (1990) A clinician rating scale for assessing current and lifetime PTSD: the CAPS-1. Behav Therap 13:187–188

    Google Scholar 

  6. Blanchard EB, Hickling EJ, Forneris CA, Taylor AE, Buckley TC, Loos WR, Jaccard J (1997) Prediction of remission of acute posttraumatic stress disorder in motor vehicle accident victims. J Trauma Stress 10:215–234

    PubMed  CAS  Google Scholar 

  7. Blanchard EB, Jones-Alexander J, Buckley TC, Forneris CA (1996) Psychometric properties of the PTSD checklist (PCL). Behav Res Ther 34:669–673

    Article  PubMed  CAS  Google Scholar 

  8. Boscarino JA, Adams RE (2009) PTSD onset and course following the World Trade Center disaster: findings and implications for future research. Soc Psychiatry Psychiatr Epidemiol 44:887–898

    Article  PubMed  Google Scholar 

  9. Breslau N (2001) Outcomes of posttraumatic stress disorder. J Clin Psychiatr 62(Suppl 17):55–59

    Google Scholar 

  10. Breslau N (2001) The epidemiology of posttraumatic stress disorder: what is the extent of the problem? J Clin Psychiatr 62:16–22

    Google Scholar 

  11. Breslau N, Chase GA, Anthony JC (2002) The uniqueness of the DSM definition of post-traumatic stress disorder: implications for research. Psychol Med 32:573–576

    Article  PubMed  CAS  Google Scholar 

  12. Breslau N, Davis GC (1992) Posttraumatic stress disorder in an urban population of young adults: risk factors for chronicity. Am J Psychiatr 149:671–675

    PubMed  CAS  Google Scholar 

  13. Breslau N, Reboussin BA, Anthony JC, Storr CL (2005) The structure of posttraumatic stress disorder: latent class analysis in 2 community samples. Arch Gen Psychiatry 62:1343–1351

    Article  PubMed  Google Scholar 

  14. Carty J, O’Donnell ML, Creamer M (2006) Delayed-onset PTSD: a prospective study of injury survivors. J Affect Disord 90:257–261

    Article  PubMed  Google Scholar 

  15. Ehlers A, Mayou RA, Bryant B (1998) Psychological predictors of chronic posttraumatic stress disorder after motor vehicle accidents. J Abnorm Psychol 107:508–519

    Article  PubMed  CAS  Google Scholar 

  16. First MB, Spitzer RL, Gibbon M, Williams JB (1996) Structured clinical interview for DSM-IV axis I disorders—patient edition (SCID-I/P, Version 2.0). Biometrics Research Department, New York State Psychiatric Institute, New York

  17. Green BL, Lindy JD, Grace MC, Gleser GC, Leonard AC, Korol M, Winget C (1990) Buffalo Creek survivors in the second decade: stability of stress symptoms. Am J Orthopsychiatr 60:43–54

    Article  CAS  Google Scholar 

  18. Johnson SD, North CS, Smith EM (2002) Psychiatric disorders among victims of a courthouse shooting spree: a three-year follow-up study. Comm Ment Health J 38:181–194

    Article  Google Scholar 

  19. Karamustafalioglu OK, Zohar J, Guveli M, Gal G, Bakim B, Fostick L, Karamustafalioglu N, Sasson Y (2006) Natural course of posttraumatic stress disorder: a 20-month prospective study of Turkish earthquake survivors. J Clin Psychiatry 67:882–889

    Article  PubMed  Google Scholar 

  20. Kessler RC, Sonnega A, Bromet E, Hughes M, Nelson CB (1995) Posttraumatic stress disorder in the National Comorbidity Survey. Arch Gen Psychiatry 52:1048–1060

    Article  PubMed  CAS  Google Scholar 

  21. Koren D, Arnon I, Klein E (2001) Long term course of chronic posttraumatic stress disorder in traffic accident victims: a three-year prospective follow-up study. Behav Res Ther 39:1449–1458

    Article  PubMed  CAS  Google Scholar 

  22. Kupchik M, Strous RD, Erez R, Gonen N, Weizman A, Spivak B (2007) Demographic and clinical characteristics of motor vehicle accident victims in the community general health outpatient clinic: a comparison of PTSD and non-PTSD subjects. Depress Anxiety 24:244–250

    Article  PubMed  Google Scholar 

  23. Maes M, Delmeire L, Schotte C, Aleksander J, Creten T, Mylle J, Struyf A, Pison G, Rousseeuw PJ (1998) Epidemiologic and phenomenological aspects of post-traumatic stress disorder: DSM-III-R diagnosis and diagnostic criteria not validated. Psychiatr Res 81:179–193

    Article  CAS  Google Scholar 

  24. McMillen JC, North CS, Smith EM (2000) What parts of PTSD are normal: intrusion, avoidance, or arousal? Data from the Northridge, California earthquake. J Trauma Stress 13:57–75

    Article  PubMed  CAS  Google Scholar 

  25. Norris FH, Friedman MJ, Watson PJ (2002) 60,000 Disaster victims speak: Part II. Summary and implications of the disaster mental health research. Psychiatry 65:240–260

    PubMed  Google Scholar 

  26. Norris FH, Friedman MJ, Watson PJ, Byrne CM, Diaz E, Kaniasty K (2002) 60,000 Disaster victims speak: Part I. An empirical review of the empirical literature, 1981–2001. Psychiatry 65:207–239

    PubMed  Google Scholar 

  27. North CS (2012) An exploration of causality in the development and timing of disaster-related PTSD. In: Widom CS (ed) Psychopathology and violence, chap 9. Oxford University Press, New York, pp 219–230

  28. North CS, Hong BA, Surís A, Spitznagel EL (2008) Distinguishing distress and psychopathology among survivors of the Oakland/Berkeley firestorm. Psychiatry 71:35–45

    PubMed  Google Scholar 

  29. North CS, Kawasaki A, Spitznagel EL, Hong BA (2004) The course of PTSD, major depression, substance abuse, and somatization after a natural disaster. J Nerv Ment Dis 192:823–829

    Article  PubMed  Google Scholar 

  30. North CS, Nixon SJ, Shariat S, Mallonee S, McMillen JC, Spitznagel EL, Smith EM (1999) Psychiatric disorders among survivors of the Oklahoma city bombing. JAMA 282:755–762

    Article  PubMed  CAS  Google Scholar 

  31. North CS, Oliver J, Pandya A (2012) Examining a comprehensive model of disaster-related PTSD in systematically studied survivors of ten disasters. Am J Public Health 102:e40–e48

    Google Scholar 

  32. North CS, Pfefferbaum B (2002) Research on the mental health effects of terrorism. JAMA 288:633–636

    Article  PubMed  Google Scholar 

  33. North CS, Pfefferbaum B, Kawasaki A, Lee S, Spitznagel EL (2011) Psychosocial adjustment of directly exposed survivors 7 years after the Oklahoma city bombing. Compr Psychiatry 52:1–8

    Article  PubMed  Google Scholar 

  34. North CS, Ringwalt CL, Downs D, Derzon J, Galvin D (2011) Postdisaster course of alcohol use disorders in systematically studied survivors of 10 disasters. Arch Gen Psychiatry 68:173–180

    Article  PubMed  Google Scholar 

  35. North CS, Smith EM, McCool RE, Lightcap PE (1989) Acute post-disaster coping and adjustment. J Trauma Stress 2:353–360

    Article  Google Scholar 

  36. North CS, Smith EM, McCool RE, Shea JM (1989) Short-term psychopathology in eyewitnesses to mass murder. Hosp Comm Psychiatr 40:1293–1295

    CAS  Google Scholar 

  37. North CS, Smith EM, Spitznagel EL (1994) Posttraumatic stress disorder in survivors of a mass shooting. Am J Psychiatr 151:82–88

    PubMed  CAS  Google Scholar 

  38. North CS, Surís AM, Davis M, Smith RP (2009) Toward validation of the diagnosis of posttraumatic stress disorder. Am J Psychiatr 166:1–8

    Article  Google Scholar 

  39. Perkonigg A, Pfister H, Stein MB, Hofler M, Lieb R, Maercker A, Wittchen HU (2005) Longitudinal course of posttraumatic stress disorder and posttraumatic stress disorder symptoms in a community sample of adolescents and young adults. Am J Psychiatr 162:1320–1327

    Article  PubMed  Google Scholar 

  40. Robins LN, Cottler LB, Compton WM, Bucholz K, North CS, Rourke KM (2000) Diagnostic interview schedule for the DSM-IV (DIS-IV). Washington University, St. Louis

    Google Scholar 

  41. Robins LN, Helzer JE, Cottler L, Goldring E (1989) NIMH diagnostic interview schedule, version III-revised. Washington University, St. Louis

    Google Scholar 

  42. Robins LN, Smith EM (1983) The diagnostic interview schedule/disaster supplement. Washington University, St. Louis

    Google Scholar 

  43. Schnurr PP, Lunney CA, Sengupta A (2004) Risk factors for the development versus maintenance of posttraumatic stress disorder. J Trauma Stress 17:85–95

    Article  PubMed  Google Scholar 

  44. Smid GE, Mooren TT, van der Mast RC, Gersons BP, Kleber RJ (2009) Delayed posttraumatic stress disorder: systematic review, meta-analysis, and meta-regression analysis of prospective studies. J Clin Psychiatry 70:1572–1582

    Article  PubMed  Google Scholar 

  45. Smith EM, North CS, McCool RE, Shea JM (1990) Acute postdisaster psychiatric disorders: identification of persons at risk. Am J Psychiatr 147:202–206

    PubMed  CAS  Google Scholar 

  46. World Health Organization (1990) Composite international diagnostic interview. World Health Organization, Geneva

    Google Scholar 

  47. Zlotnick C, Rodriguez BF, Weisberg RB, Bruce SE, Spencer MA, Culpepper L, Keller MB (2004) Chronicity in posttraumatic stress disorder and predictors of the course of posttraumatic stress disorder among primary care patients. J Nerv Ment Dis 192:153–159

    Article  PubMed  Google Scholar 

  48. Zlotnick C, Warshaw M, Shea MT, Allsworth J, Pearlstein T, Keller MB (1999) Chronicity in posttraumatic stress disorder (PTSD) and predictors of course of comorbid PTSD in patients with anxiety disorders. J Trauma Stress 12:89–100

    Article  PubMed  CAS  Google Scholar 

Download references

Acknowledgments

This research was supported by National Institute of Mental Health Grant MH40025 to Dr. North.

Conflict of interest

Dr. North acknowledges employment at VA North Texas Health Care System. Points of view in this document are those of the author(s) and do not necessarily represent the official position of the Department of Veterans Affairs or the United States Government. Dr. North also discloses research support from NIAAA, NIDDK, the Department of Veterans Affairs, the American Psychiatric Association, and the Orthopaedic Trauma Association, and consultant fees from the University of Oklahoma Health Sciences Center and from the Tarrant County, TX Department of Health. Ms. Oliver reports no disclosures.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Carol S. North.

Rights and permissions

Reprints and permissions

About this article

Cite this article

North, C.S., Oliver, J. Analysis of the longitudinal course of PTSD in 716 survivors of 10 disasters. Soc Psychiatry Psychiatr Epidemiol 48, 1189–1197 (2013). https://doi.org/10.1007/s00127-012-0639-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00127-012-0639-x

Keywords

Navigation