Melatonin - MeSH

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Items: 15

Select item 680085501.

A biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood, and REPRODUCTION. Melatonin is also an effective antioxidant.

Year introduced: 1968(1965)

Select item 680441232.

Receptor, Melatonin, MT2

A melatonin receptor subtype primarily found expressed in the BRAIN and RETINA.

Year introduced: 2004

Select item 680441223.

Receptor, Melatonin, MT1

A melatonin receptor subtype that is primarily found in the HYPOTHALAMUS and in the KIDNEY.

Year introduced: 2004

Select item 680440944.

Receptors, Melatonin

A family of G-protein-coupled receptors that are specific for and mediate the effects of MELATONIN. Activation of melatonin receptors has been associated with decreased intracellular CYCLIC AMP and increased hydrolysis of PHOSPHOINOSITIDES.

Year introduced: 2004

Select item 675767455.

melatonin 1a receptor, Xenopus [Supplementary Concept]

Date introduced: December 12, 2012

Select item 675767446.

melatonin 1b receptor, Xenopus [Supplementary Concept]

Date introduced: December 12, 2012

Select item 675738717.

MTNR1B protein, human [Supplementary Concept]

the rs10830963 variant is associated with increased risk for gestational diabetes mellitus in a Greek population; RefSeq NM_005959

Date introduced: July 27, 2012

Select item 675268888.

N-(4-chlorobenzoyl)melatonin [Supplementary Concept]

an indomethacin analog that is a selective inhibitor of aldo-keto reductase 1C3 (type 2 3alpha-HSD, type 5 17beta-HSD, and prostaglandin F synthase); a potential target for the treatment of hormone dependent and hormone independent malignancies; structure in first source

Date introduced: February 28, 2008

Select item 675097549.

GPR50 protein, human [Supplementary Concept]

RefSeq NM_004224

Date introduced: August 4, 2006

Select item 6707289010.

melatonin deacetylase [Supplementary Concept]

enzyme from various vertebrate ocular tissues converts melatonin to 5-hydroxytryptamine

Date introduced: March 16, 1992

Select item 6705451311.

6-sulfatoxymelatonin [Supplementary Concept]

metabolite of melatonin; RN given refers to parent cpd