https://www.ndm.ox.ac.uk/news The latest news, updates and announcements from the Nuffield Department of Medicine.enHaikuResearch on sickle cell disease conducted by KEMRI-Wellcome Trust Research Programme (KWTRP) at the Nuffield Department of Medicine shows significant progress in understanding how to improve survival rates and quality of life for those living with the condition.https://www.ndm.ox.ac.uk/news/improving-survival-rates-of-children-with-sickle-cell-disease-in-kenya Thu, 19 Sep 2024 12:16:44 +0100https://www.ndm.ox.ac.uk/news/improving-survival-rates-of-children-with-sickle-cell-disease-in-kenyaA recent study identified key factors contributing to the tuberculosis burden in Ho Chi Minh City, conducted by researchers from the Oxford University Clinical Research Unit in Vietnam (OUCRU), part of the Nuffield Department of Medicine, and Pham Ngoc Thach Hospital.https://www.ndm.ox.ac.uk/news/central-ho-chi-minh-city-identified-as-a-hotspot-for-tuberculosis Wed, 18 Sep 2024 14:40:00 +0100https://www.ndm.ox.ac.uk/news/central-ho-chi-minh-city-identified-as-a-hotspot-for-tuberculosisBased on estimates across 204 countries and territories, new forecasts from the Global Research on Antimicrobial Resistance (GRAM) Project suggest that bacterial antimicrobial resistance (AMR) will cause 39 million deaths between 2025 and 2050 – equating to three deaths every minute.https://www.ndm.ox.ac.uk/news/antibiotic-resistance-could-cause-39-million-deaths-between-now-and-2050 Tue, 17 Sep 2024 16:39:48 +0100https://www.ndm.ox.ac.uk/news/antibiotic-resistance-could-cause-39-million-deaths-between-now-and-2050Four years after being derailed by scientific fraud and politicised science in the first year of the pandemic, COPCOV, the world’s largest COVID-19 chemoprevention study, finally published results today that showed that hydroxychloroquine (HCQ) does have a moderate benefit in preventing COVID-19.https://www.ndm.ox.ac.uk/news/hydroxychloroquine-provides-moderate-covid-19-prevention Mon, 16 Sep 2024 10:58:00 +0100https://www.ndm.ox.ac.uk/news/hydroxychloroquine-provides-moderate-covid-19-preventionResearchers in the Nuffield Department of Medicine, supported by NIHR Oxford Biomedical Research Centre (BRC), have discovered a link between potentially pathogenic bacteria and airways inflammation in people with severe asthma.https://www.ndm.ox.ac.uk/news/new-study-improves-understanding-of-lung-microbiome-in-severe-asthma-patients Thu, 12 Sep 2024 00:00:00 +0100https://www.ndm.ox.ac.uk/news/new-study-improves-understanding-of-lung-microbiome-in-severe-asthma-patientsScientists from the Centre for Human Genetics at Nuffield Department of Medicine are taking the initial steps in developing the UK’s first vaccine to prevent cancer in people with Lynch syndrome, thanks to funding from Cancer Research UK.https://www.ndm.ox.ac.uk/news/developing-the-first-cancer-prevention-vaccine-for-lynch-syndrome Tue, 10 Sep 2024 15:02:00 +0100https://www.ndm.ox.ac.uk/news/developing-the-first-cancer-prevention-vaccine-for-lynch-syndromeThe Van den Eynde groups at the Ludwig Institute for Cancer Research in Brussels and Oxford have demonstrated that deletion of PHD2/3 enzymes in CD8 T cells shows an enhanced tumour response in various cancer models.https://www.ndm.ox.ac.uk/news/adoptive-t-cell-therapy-shows-an-enhanced-tumour-response Mon, 09 Sep 2024 12:19:00 +0100https://www.ndm.ox.ac.uk/news/adoptive-t-cell-therapy-shows-an-enhanced-tumour-responseResearchers at the University of Oxford and the University of Liverpool have for the first time been able to estimate the current burden of Lassa fever, project the impacts of a Lassa fever vaccination programme, and demonstrate how it may help avoid the next pandemic.https://www.ndm.ox.ac.uk/news/preventive-vaccination-could-be-a-key-strategy-against-lassa-fever-and-the-next-pandemic Thu, 29 Aug 2024 09:00:00 +0100https://www.ndm.ox.ac.uk/news/preventive-vaccination-could-be-a-key-strategy-against-lassa-fever-and-the-next-pandemicScientists have developed a first-of-its-kind mass spectrometry method for vaccine authenticity screening using machine learning. The method repurposes clinical mass spectrometers already present in hospitals worldwide, making the approach feasible for global supply chain monitoring. The discovery offers an effective solution to the rise in substandard and counterfeit vaccines threatening public health.https://www.ndm.ox.ac.uk/news/scientists-develop-new-method-to-detect-fake-vaccines Wed, 28 Aug 2024 14:35:00 +0100https://www.ndm.ox.ac.uk/news/scientists-develop-new-method-to-detect-fake-vaccinesWe are delighted to announce that ten researchers have been awarded the title of Professor, in recognition of their research achievements, contribution to teaching, and contribution to the general work of the Nuffield Department of Medicine.https://www.ndm.ox.ac.uk/news/ten-ndm-researchers-awarded-full-professorships Thu, 22 Aug 2024 15:08:55 +0100https://www.ndm.ox.ac.uk/news/ten-ndm-researchers-awarded-full-professorshipsThe Faculty of Medicine Universitas Indonesia (FMUI) and OUCRU Indonesia have completed a phase 2 clinical trial for two new malaria vaccines developed by Sanaria Inc. This is the first malaria vaccine trial ever conducted in Indonesia and the first in the Asia-Pacific region in over 30 years.https://www.ndm.ox.ac.uk/news/oucru-and-universitas-indonesia-complete-historic-malaria-vaccine-trial Mon, 19 Aug 2024 10:00:00 +0100https://www.ndm.ox.ac.uk/news/oucru-and-universitas-indonesia-complete-historic-malaria-vaccine-trialThe Pandemic Sciences Institute, in collaboration with the Ethox Centre, has supported a new exhibition at Oxford’s History of Science Museum. The exhibition, entitled "A Healthy Future for All?", explores the science driving advancements in healthcarehttps://www.ndm.ox.ac.uk/news/psi-collaborates-with-history-of-science-museum-on-new-exhibition Mon, 12 Aug 2024 10:00:00 +0100https://www.ndm.ox.ac.uk/news/psi-collaborates-with-history-of-science-museum-on-new-exhibitionDéirdre Hollingsworth, Professor of Infectious Disease Epidemiology at the University of Oxford, has been awarded a prestigious Simons Foundation Fellowship from the Isaac Newton Institute. This recognition supports her efforts in using mathematical modelling to improve global health outcomes. As part of this initiative, Déirdre is organizing a one-day event on August 13, 2024, focusing on pandemic preparedness. The event aims to address key policy questions through mathematical modelling, covering vaccine development, diagnostics and funding.https://www.ndm.ox.ac.uk/news/professor-deirdre-hollingsworth-receives-simons-foundation-fellowship Mon, 05 Aug 2024 10:00:00 +0100https://www.ndm.ox.ac.uk/news/professor-deirdre-hollingsworth-receives-simons-foundation-fellowshipA ground-breaking study, published by the New England Journal of Medicine, has identified a new disease-inducing mechanism for inflammatory bowel disease (IBD) in which the immune system attacks its own regulatory function.https://www.ndm.ox.ac.uk/news/new-research-identifies-autoimmunity-against-a-key-anti-inflammatory-regulator Sun, 04 Aug 2024 10:00:00 +0100https://www.ndm.ox.ac.uk/news/new-research-identifies-autoimmunity-against-a-key-anti-inflammatory-regulatorProfessor Sassy Molyneux has received a prestigious five-year NIHR Global Health Research Professorship to study how to better protect frontline staff in international health research from moral distress. This is one of only five to seven such `flagship’ professorships awarded by the NIHR each year to outstanding scientists.https://www.ndm.ox.ac.uk/news/professor-sassy-molyneux-awarded-nihr-global-health-research-professorship Fri, 02 Aug 2024 10:00:00 +0100https://www.ndm.ox.ac.uk/news/professor-sassy-molyneux-awarded-nihr-global-health-research-professorship